Home Tools
Log in
Cart

Search Result

Search Results for " kidney disease "

20

Compounds

Cat No. Product Name Synonyms Targets
T2S1837 Steviol NSC 226902,Hydroxydehydrostevic acid Others
1. Steviol (NSC-226902), a natural sweetener, it inhibits proliferation of the gastrointestinal cancer cells intensively. 2. Steviol can induce a significant increase in CYP3A29 expression. 3. Steviol inhibits the prolif...
T14002 12-Ketodeoxycholic acid Endogenous Metabolite
12-Ketodeoxycholic acid, a bile acid and kidney metabolite, serves as a detectable marker for kidney injury [1].
T7802 M1001 HIF/HIF Prolyl-Hydroxylase , HIF
M1001 is a HIF-2α agonist.
T8528 AC1903 TRP/TRPV Channel
AC1903 is a specific inhibitor of TRPC5 channel, and has been shown to suppress severe proteinuria and prevent podocyte loss.
T11394 GFB-8438 TRP/TRPV Channel
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).
T9022 AZD9977 AZD 9977 Glucocorticoid Receptor
AZD9977 is a novel, selective modulator of mineralocorticoid receptor .
T1874 PPQ-102 PPQ102,CFTR Inhibitor,PPQ 102 CFTR , Autophagy
PPQ-102 (CFTR Inhibitor), an effective CFTR inhibitor, can completely inhibit CFTR chloride current (IC50: 90 nM).
T4583 PFI-2 hydrochloride (R)-PFI-2 hydrochloride,PFI-2 HCl Histone Methyltransferase
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.
T1615 Irbesartan SR-47436,BMS-186295 Apoptosis , RAAS
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
T21395 Finerenone BAY948862,BAY-948862,BAY94-8862,BAY 94-8862,BAY-94-8862,BAY 948862 Glucocorticoid Receptor
Finerenone (BAY-948862) is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist with IC50 of 18 nM for the treatment of chronic heart failure. Finerenone (BAY-948862...
T6666 Sevelamer Carbonate Others
Sevelamer carbonate is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion.
T1987 PFI-2 PFI2,PFI 2,(R)-PFI-2 Histone Methyltransferase
PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
T40108 Inaxaplin VX-147 Others
Inaxaplin is an apolipoprotein L1 ( APOL1 ) function inhibitor. Inaxaplin can be used for the research of kidney disease.
T13591 Calcium polystyrene sulfonate Poly(styrenesulfonic acid) calcium salt Others
Calcium polystyrene sulfonate (Poly(styrenesulfonic acid) calcium salt) is an ion-exchange resin. Calcium polystyrene sulfonate reduces blood levels of potassium and can be used for research on the treatment of hyperkale...
T0080 Trapidil Rocornal,Trapymine,Avantrin,Trapymin,AR-12008 PDGFR , PDE
Trapidil (Avantrin) is a coronary vasodilator agent. It was originally developed as a vasodilator and anti-platelet agent and has been used to treat patients with ischemic coronary heart, liver, and kidney disease.
T77364 Sibeprenlimab VIS649,VIS-649 Others
Sibeprenlimab (VIS649) is a humanized IgG 2 monoclonal antibody that suppresses APRIL. Sibeprenlimab has an inhibitory effect on APRIL and may be studied for the prevention and treatment of kidney disease (IgAN).
T21977 P-Cresyl sulfate Others
p-Cresyl Sulfate is a major uremic toxin found in the blood of patients with chronic kidney disease (CKD), derived from the metabolites of tyrosine and phenylalanine in the liver.
T5623 Bisphenol A Others , Endogenous Metabolite
Bisphenol A is an endogenous metabolic compound of phenols and is widely used in the production of epoxy resins and polycarbonate plastics. It is reproductive, developmental and systemic toxicant and is often classified ...
T40109 APOL1-IN-1 APOL1-IN-1 Others
APOL1-IN-1 is a potent inhibitor of apolipoprotein L1 (APOL1) that can be used to study the pathogenesis of focal segmental glomerulosclerosis (FSGS) and nondiabetic kidney disease (NDKD), facilitating research into thes...
T60170 BLU2864 Others
BLU2864 is an orally active, highly selective, ATP-competitive PRKACA inhibitor with IC 50 of 0.3 nM. BLU2864 exhibits anti-tumor activity. BLU2864 has potential to be used in cancer and polycystic kidney disease researc...
1 2 3 4
TargetMol